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X-LINKED INHIBITOR OF APOPTOSIS PROTEIN
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DeCS
Descriptor
English
:
X-Linked Inhibitor of Apoptosis Protein
Descriptor
Spanish
:
Proteína Inhibidora de la Apoptosis Ligada a X
Descriptor
Portuguese
:
Proteínas Inibidoras de Apoptose Ligadas ao Cromossomo X
Tree Number:
D12.644.360.075.437.750
D12.776.476.075.437.750
Definition
English
:
An inhibitor of
apoptosis
protein that is translated by a rare cap-independent mechanism. It blocks caspase-mediated cellular destruction by inhibiting
CASPASE 3
;
CASPASE 7
; and
CASPASE 9.
Pharmacological Action:
Caspase Inhibitors
History Note
English
:
2006(1996)
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DU
diagnostic use
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
50804
Unique Identifier:
D051636
Occurrence in VHL
:
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